ITEM NO.: FS01-A069KS
[DRUG NAME] Generic Name: Cefpiramide for Injection
[INDICATIONS] It is indicated for the treatment of the following infections caused by sensitive bacteria of Staphylococcus aureus, STREP (except enterococci), Streptococcus anaerobius, Bacillus coli, Citrobacter, Klebsiella Cedecea, Proteus, Proteus, morganii, Pseudomonas, Hemophilus influenza, Acinetobacter, and Bacteroide: 1) septicoemia; 2) secondary infection in burns and operative incisions; 3) laryngopharyngitis (abscess in throad), acute bronchitis, amygdatitis (periamygdalitis, circumtonsillar abscess), chronic bronchitis, bronchiectasis (in fection), secondary infection of chronic respiratory diseases, pneumonia, pulmonary abscess, and empyema; 4) endonephritis, angiocholitis; 5) peritonitis including pelvic peritonitis, dellen abscess in bladder and rectum; 6)adnexitis, intrauterine infections, pelvic inflammation, infections in latero-uterus connective tissue, bartholinitis; 7) meningitis; 8) infections in jaw joint, cellutitis around jaw bones.
[INGREDIENTS] The main composition is cefpiramide.
[DESCRIPTION] White to yellowish powder.
[PHARMACOLOGY] 1. Antibacterial activity:
(1) Strong antibacterial activity against Gram-positive bacteria and non-glucose ferment Gram-negative bacillus including pyocyaneum bacteria as well as broad-spectrum antibacterial activity against bacteria including Gram-negative bacteria. This drug is an anti-bacteria agent and has stability in the presence ofβ-lactamases produced by all kinds of bacteria.
(2) Good therapeutic efficacy when used in experimental infection in mice.
(3) Bacteria resistant to antibiotics like penicillins, other cephalosporins and aminoglcoside, especially pyocyaneum bacterium are susceptible to this product.
2. Mechanism of action
It has very strong affinity with 1A, 2B and 3 of PBP to inhibit the composition of cytoderm in bacteria, in which way bacteria are killed.
[DOSAGE AND ADMINISTRATION] The usual adult daily dose is 1~2g per day divided into 2 administrations by intravenous injections or intervenous drop infusions; In refractory or severe infections, a total daily dosage of 4g is divided into 2 or 3 administrations by intervenous drop infusions according to specific symptoms. The usual children daily dose is 30~80mg/kg (body weight)/day divided into 2~3 administrations by intervenous drop infusions; In refractory or severe infections, a total daily dosage of 150mg/kg (body weight)/day is divided into 2~3 intervenous drop infusions according to specific symptoms.
[SPECIFICATION] 1g (C25H24N8O7S2)
[PACKAGE] 1 bottle/box (pharmacy bottle used for antibiotics)
[STORAGE] Keep tightly closed. Protect from direct light and store in a cool dry place.
[SHELF-LIFE] 24 months.
Model: FS01-A069KS
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